mrbait: Universal identification and design of targeted-enrichment capture probes¶
mrbait is a software pipeline for identifying regions of interest in DNA sequence data and designing probes to enrich them.
The motivation behind mrbait is ease and flexibility of use. As such, mrbait allows a variety of input types and facilitates a diverse array of bait design approaches, such as those targeting ultraconserved elements, RAD-capture methods, or those targeting exons or other genomic elements. mrbait also enables fast and efficient iterative design (e.g. to explore parameter settings) using native Python parallelization and an SQL database back-end. In this documentation, you can learn about the overall process employed by mrbait (Pipeline overview), how to install mrbait for use on a personal desktop or remote workstation or HPC (Getting Started), see a full description of all runtime options (Running mrbait), and see walltime and memory benchmarking results (Benchmarking)
mrbait code is open-source and freely available at on GitHub
Official releases can be found here
Having issues running or installing mrbait? Contact me at tkchafin@uark.edu or post an Issue on the GitHub page.
- Citation: Chafin TK, Douglas MR, Douglas ME (2018) MrBait: Universal
- identification and design of targeted-enrichment capture probes. Bioinformatics. https://doi.org/10.1093/bioinformatics/bty548
Software and documentation provided under the GNU Public License v3.0 and distributed “as is” without warranty of any kind.